We have our "what the heck happened" appointment next Tuesday. And (I am such a nerd) I've been looking up research articles on poor IVF response. What I've learned is that they define poor response based up on:
- The number of eggs retrieved (poor = <4)
- The amount of stims given per day (poor = greater than or = to 300 IU/d)
- The total amount of stims given in the cycle (poor = greater than or = to 3000 IU/cycle)
- And a cancelled cycle
- 7 eggs retrieved of which 6 were mature
- I took 225 IU of stims each day
- In total I took 2250 IU/cycle
- And we were not cancelled
So basically I think I just squeaked by a 'poor' response cycle and I think there is a good chance that my 'poor response' was that I was not on the right meds. That or I was totally over suppressed by the Lupron. I mean, hello, I started off with an E2 of LESS THAN 7!!! Does anyone else find that ridiculously low when they are just looking for anything below 80?
I also looked up poor response to IVF stims due to ovarian edometriosis. This is when endometriosis is found on an ovary. The effects are usually a smaller amount of follicles, typically on the side of the endometrioma, and a poor response in general with fewer follicles and fewer mature eggs retrieved. But in reading up on this I don't think I totally fit that picture either. What they found during my lap was:
- one spot of endometriosis on my right ovary (which was causing all my pain), and
- one spot on the back of my uterus
My GYN who did the surgery said I didn't even meet the qualifications for Mild endometriosis and that if there was a 'very mild' she'd 'think' about putting me in that category. Basically, she didn't think it was causing our infertility but is glad that my right side pain went away with the removal of the ovarian endometroma. And let's all keep in mind that if my right ovary is supposed to be 'effected' by my endometriosis it's always:
- Had the largest follicles (except this last cycle)
- The highest number of follicles
- And this round of the cycle had the most mature eggs retrieved
So righty defies all logic of an ovary effected by endometriosis. (Way to go righty!) Now lefty has always been a quandary because it does not always participate and then some times it surprises us, like this last cycle, and decides to pop out the best looking follicles of the bunch. But it still failed to produced large amounts of follicles. That is why I'm wondering if I was either sensitive to the Lupron or Bravelle was just not the drug for me.
I'm excited to try a new set of drugs to see how I do. And I don't know about you but I think 6 mature eggs when I only had 4 mature sized follicles is pretty darn awesome! Plus we made it to transfer once before which means we have a really good chance of doing it again. That and we just got word that Hammer will be getting a bonus in the amount that will cover our drugs! This part was a total shock to us but it could not have come at a better time when we were just trying to plan out fiscally what we were going to pull from to do the next cycle. Hammer is actually in corporate finance so we are well managed $-wise to do another cycle but it takes off some pressure and every penny saved means more in our savings and the longer I can stay home with our future baby(ies).
My favorite part about all this is that it looks like we'll start cycling again at the end of August. Which means that we will be doing BCP and Lupron (?) in September with a retrieval/transfer some time in October. And October is when our Florida vaca was cancelled because my work is not letting anyone travel in October. So now with a looming Oct IVF on the horizon we wouldn't be heading south anyway. Originally, I choose to let Hammer be mad for the both of us about our cancelled vacation because I didn't want to add more stress on our first IVF which was a good idea in more ways than one. I didn't hold a grudge and now I actually have to thank the head of my department because we can jump right into another try.
So I'm armed and ready with my list of questions for Dr. F and feeling good about Operation Hammer Babies Take Two!